Analysis of Disinfectant with Aldehyde
Since disinfectants and antiseptics have microbicide and microbiostatic effects on microorganisms, they have become products that we use frequently in the field of medicine and in our daily life due to the pandemic.In particular, disinfectants used in hospitals and clinics should be suitable for the area where they are used and against the microorganism to be affected. In addition to the minimal inhibition concentration, we can say that the type of germicide, contact time and concentration determine the effectiveness of a disinfectant. Considering the area to be used, the risk of infection should be taken into account in the selection of disinfection.
One of the important disinfectant types is "Aldehyde Disinfectants". Aldehyde disinfectants may contain Gluteraldehyde, Ortho-Phthaldehyde (OPA), Formaldehyde and Ethylene oxide.
Gluteraldehyde and formaldehyde are among the most commonly used aldehydes. Glyoxal, ortho-phthaldehid (OPA), succinaldehyde and benzaldehyde are other aldehydes with sterilizing effects.
Glutaraldehyde; It can be used in chemical sterilization and high-level disinfection due to its high potency and non-corrosive effect. With a pH of 7.5-8.5, 2% standard glutaraldehyde can be used as bactericidal, tuberculocidal, fungicidal, virucidal and sporicidal.
Ortho-Phthaldehid (OPA); It does not need to be activated before use and it is preferred that it does not lose its effectiveness during storage, does not have an effective odor and does not cause irritation to the eyes and respiratory system. In addition, in-vitro mycobactericidal effect is more than glutaraldehyde.
Formaldehyde; disinfectant and sterilant were used, but later it was banned in the USA and England due to its toxic and carcinogenic effects. The Occupational Safety and Health Administration stated that it can be used in a working environment, provided that it does not exceed 0.75 ppm for 8 hours of work.
Ethylene oxide; A mixture of carbon dioxide and/or hydrofluorocarbons is the most commonly used form. It is a microbicide and sproicide. Concentrations above 3.6% have a flammable, explosive gas feature.
In order to prove their effectiveness in aldehyde disinfectants and to determine their usage areas, they should be analyzed in authorized laboratories.
